News

Announcements

Pew

Mitch Guttman is named a Pew-Steward Scholar for cancer research. Read more at Pew and Caltech

Sloane

Mitch Guttman is named a Alfred P. Sloan fellow in computational and evolutionary molecular biology. Read more.

EIA

Mitch Guttman is awarded the 2012 NIH Director’s Early Independence Award. Read more

In The News

New roles emerge for non-coding RNAs in directing embryonic development

New roles emerge for non-coding RNAs in directing embryonic development

Broad scientists discovered several years ago that the human and mouse genomes encode thousands of unusual RNAs — termed large, intergenic non-coding RNAs (lincRNAs) —but their role was almost entirely unknown. By studying more than 100 lincRNAs in ES cells, the researchers now show that these RNAs help regulate development by physically interacting with proteins to coordinate gene expression and suggest that lincRNAs may play similar roles in most cells.

Read more at here

Missing links of the transcriptome

Missing links of the transcriptome

Despite the many discoveries of the genomic era, much of the human genome remains unexplored. Researchers have now discovered the identity of some of those unknown players and introduce a vast new class of genomic characters that function directly as RNA molecules.

Read more here

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