Guttman lab celebrates a happy return to our favorite tradition, the annual lab retreat. This year’s event was held December 10-12 in the mountain town of Lake Arrowhead, California. Lab members presented their work, discussed next year’s goals and opportunities, and drew out a roadmap for another year of research. But that’s not all, we took plenty of time to relax, hike, and make s’mores in this idyllic mountain setting.
New paper now published to Nature Biotechnology: “Single-cell measurement of higher-order 3D genome organization with scSPRITE”. This new application of our SPRITE methods measures multi-way DNA interactions around nuclear bodies, TADs, and P-E in hundreds of mouse embryonic stem cells. Read the Paper here
Guttman lab’s Nature Reviews article discussing the role of nuclear compartmentalization is out now. Titled “Nuclear compartmentalization as a mechanism of quantitative control of gene expression”, read the full text here
Welcome Noah Epstein! Noah joins our lab as a graduate student and is interested in studying nuclear compartmentalization.
Welcome Olivia Ettlin! We’re thrilled to have Olivia join us as Guttman Lab’s newest Technician-Assistant.
Congratulations to our newest graduate Abhik Banerjee! We will miss you and we look forward to seeing what exciting things await you!
Welcome Isabel Goronzy! Isabel has joined Guttman Lab as a MD/PhD graduate student.
Guttman Lab has moved! We’re now making ourselves at home in the brand new Chen Neuroscience Research Building, a beautiful open-space center constructed with scientific collaboration in mind. Learn more about the space
Mario Blanco is featured in Faces of Cell for his work in “SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses“. Learn more
Our latest work “SARS-CoV-2 Disrupts Splicing, Translation, and Protein Trafficking to Suppress Host Defenses” is published with Cell. Read the full text at Cell.com
In The News
Featured this week in Caltech News: Using the latest innovation developed at Guttman Lab, RNA-DNA SPRITE, our team discovered that non-coding RNA create “compartments” within the nucleus and shepherd key molecules to precise regions in the genome. Read this review now at Caltech News
Reserved for graduate students going into their final year of doctoral work, the fellowship was created to recognize and support outstanding scholastic achievement. Read about Prashant’s work and the award at Caltech News
Caltech Professor Discovers Long Intergenic Non-coding RNA to Treat Incurable Neurodevelopmental Disorder
In an in-depth Q&A session, Professor Guttman explains the important connection between long intergenic non-coding RNAs, or lincRNAs, and X chromosome inactivation. Read the full featuered interview at TouchPoints Magazine
As a doctoral student at Guttman Lab, Sofi developed a new way to map how cells’ nuclei are organized. Read about the fellowship at HHMI
Read the article in The Scientist
Read the overview of our research at NYSCF
Read this discussion about our paper at Caltech News
Established in 2009, this award “promotes cross-cutting, interdisciplinary approaches and is open to individuals and teams of investigators who propose research that could potentially create or challenge existing paradigms.” Read more
Graduate student Sofia Quinodoz has been awarded the Harold M. Weintraub Graduate Student Award by the Fred Hutchinson Cancer Research Center. The award recognizes “outstanding achievement during graduate studies in the biological sciences.” Learn more at Caltech News