A news article in The Scientist discusses the latest research into significantly more efficient mRNA splicing based on its proximity to nuclear speckles.
“This idea that functional kinetic coupling of two very diverse but critically integrated processes is achieved through physical spatial organization, remodeling of DNA architecture, is something that I wouldn’t have necessarily anticipated,” Guttman said, “but I think it’s incredibly exciting, and more generally, in thinking about novel mechanisms of how quantitative regulation occurs in the cell.”
Read the article in The Scientist ▶︎