Oct 29, 2024 | In The News, Science Articles
A news article in The Scientist discusses the latest research into significantly more efficient mRNA splicing based on its proximity to nuclear speckles. “This idea that functional kinetic coupling of two very diverse but critically integrated processes is achieved...
May 8, 2024 | In The News, Science Articles
Featured this week in Caltech News: New work on nuclear speckles, now published in Nature, “Genome organization around nuclear speckles drives mRNA splicing efficiency”. Previously, we tended to think of splicing as a constant—you make a pre-mRNA; you...
Feb 21, 2022 | In The News, Science Articles
Nature interviews Guttman Lab in this week’s Technology Feature discussing the latest technological advances for studying 3D genome organization. In concert with the in situ microscopy renderings created at Caltech’s Cai Lab, Guttman Lab’s SPRITE method...
Jul 31, 2018 | Science Articles
“SPRITE maps the 3D genome” Nature Methods: In Brief
Jun 11, 2018 | Science Articles
“SPRITE: A Refreshing New Approach for Identifying Higher-Order Genomic Structure” EpiGenie
