Oct 29, 2024 | In The News, Science Articles
A news article in The Scientist discusses the latest research into significantly more efficient mRNA splicing based on its proximity to nuclear speckles. “This idea that functional kinetic coupling of two very diverse but critically integrated processes is achieved...
May 8, 2024 | In The News, Science Articles
Featured this week in Caltech News: New work on nuclear speckles, now published in Nature, “Genome organization around nuclear speckles drives mRNA splicing efficiency”. Previously, we tended to think of splicing as a constant—you make a pre-mRNA; you...
Feb 23, 2024 | In The News
In a recent interview on the Active Motif Epigenetics Podcast with host Dr. Stefan Dillinger, Dr. Mitch Guttman discussed exploring the long non-coding RNA Xist and its role in X chromosome inactivation, as well as his lab’s development of the SPRITE method to...
Feb 21, 2022 | In The News, Science Articles
Nature interviews Guttman Lab in this week’s Technology Feature discussing the latest technological advances for studying 3D genome organization. In concert with the in situ microscopy renderings created at Caltech’s Cai Lab, Guttman Lab’s SPRITE method...
Nov 5, 2021 | In The News
Featured this week in Caltech News: Using the latest innovation developed at Guttman Lab, RNA-DNA SPRITE, our team discovered that non-coding RNA create “compartments” within the nucleus and shepherd key molecules to precise regions in the genome. Read...
Jun 24, 2021 | In The News
Prashant Bhat awarded de Karman Fellowship. Reserved for graduate students going into their final year of doctoral work, the fellowship was created to recognize and support outstanding scholastic achievement. Read about Prashant’s work and the award at Caltech...
