SPRITE: A New Technique For Mapping DNA In Our Nuclei

Researchers at the California Institute of Technology led by NYSCF – Robertson Investigator Mitchell Guttman, PhD, have developed a new tool called SPRITE to uncover how cells organize their DNA within the nucleus. Read more at the NYSCF here

A map to the center of the cell

Researchers from the California Institute of Technology (CA,USA) have unraveled the mystery of how the genome is organized inside the nucleus. Read the article in BioTechniques

The Cartography of the Nucleus

Caltech researchers have shown how cells organize the seemingly immense genome in a clever manner so that they can conveniently find and access important genes. Understanding the delicate three-dimensional organization of the genome is crucial, particularly because...

Hushing the X Chromosome

Hushing the X Chromosome Changes to the three-dimensional structure of DNA in the nucleus are required for X-chromosome silencing, also known as X inactivation. A single molecule called Xist is responsible for the DNA remodeling, and these structural changes are...