Apr 27, 2015 | In The News
Silencing the X chromosome Scientists at Caltech developed a new approach allowing them to look at lncRNA complexes in cells and were able to identify the proteins that directly interact with the Xist RNA and, ultimately, are necessary to silence transcription of the...
Apr 27, 2015 | In The News
How an RNA Gene Silences a Whole Chromosome By studying an important lncRNA, called Xist, researchers at Caltech have discovered how an abundant class of RNA genes, called long non-coding RNAs (lncRNAs, pronounced link RNAs) can regulate key genes. The scientists...
Oct 7, 2013 | In The News, Mitch Guttman
Minding the Gaps in the Genome: An Interview with Mitch Guttman Guttman’s lab at Caltech will continue to study lncRNAs—how they work, why they are needed, and what makes them special. Guttman recently took a break from setting up his lab to answer a few...
Jul 4, 2013 | In The News
The M.O. of Unusual RNA Molecules The entire genome is coiled and folded up in any number of ways within the nucleus of each of our cells. Think, then, of the challenge that a protein or other molecule, like RNA, faces when searching through that material to locate a...
Dec 20, 2012 | In The News, Mitch Guttman
5 questions for Mitch Guttman An interview with Mitch Guttman — one of the Broad Institute’s first generation of “alumni” — who as named to the Forbes “30 Under 30: Science and Healthcare” list of rising stars. This accolade comes on the heels of another...
Aug 29, 2011 | In The News
An RNA Switch for Stem Cells A new study reveals the influence of large RNA molecules in controlling stem cells. Read more at MIT Technology Review here
